The Executive Council of Chhatrapati Shahuji Maharaj Medical University is the appointing authority to various positions in the university. Faculty and Class II appointments are made through a Selection Committee appointed by the Vice Chancellor usually comprising of the Head of Department, the Vice Chancellor and internal and external technical experts. Appointments of clerical and inferior staff are filled up through the Hospital Board of Management. Once appointed, the inservice governance of the employee is through the respective office, which maintains the Service Book of the appointee.

Interns and Resident Doctors are under the administrative control of the Superintendent, Gandhi Memorial & Associated Hospitals. Appointments of Resident Doctors is on the basis of all India competitive examination conducted by All India Institute of Medical Sciences, New Delhi for 15% of the seats and through the UP Postgraduate Medical Entrance Examination (UP PGMEE) for 85% of the seats. All Junior Residents in the hospital are registered candidates for an accredited postgraduate degree/diploma programme of the university. Besides these, nominated candidates from Armed Forces and Provincial Medical Services are admitted to certain diploma courses only. Senior Residents are appointed after post graduation through the merit of PGMEE. The university has so far not taken residents for Diplomate National Board program.

The nursing staff are governed by the Senior Matron of the hospital and belong to the Provincial Nursing Services of Uttar Pradesh.